Sarcopenia

There is an “Obesity paradox” among older Americans. This describes the unexpected finding that slightly overweight older people with a particular disease have better outcomes than their normal-weight or underweight peers.  Overweight is measured by a formula called the Body Mass Index (BMI), which measures height, weight, and age. A recent review in 2023 by Moustapha Dramé confirmed this observation that being a little overweight for older adults is beneficial. Even though obese people are more vulnerable to diseases, including an increased risk of infections, cancer, and heart disease. However, once you get a disease, having greater functional reserves might come in use. But there is a more interesting story to tell rather than simply weight.

BMI is not a good way to measure healthy body weight, especially for older adults. Once you reach 30 years of age, muscle begins to reduce. By the time we reach 70, we may have only half the muscle we had in our 20s. This is not only a function of age but a function of poor nutrition, inactivity, and a general difficulty in building muscle. Women’s menopause might also make things worse. Physicians call this Sarcopenia, the common tendency to lose muscle mass due to aging, but it does not have to be like this.

Loss of muscle mass is a serious threat to health.  It contributes to disability and frailty. In addition, studies show that there may be an association between sarcopenia and rheumatoid arthritis, falls, and even dementia. Building muscle in older age is difficult but possible. A person can only build muscle through resistance training, not just walking. We can use our own body weight (e.g., by doing push-ups and squats) and lifting household items such as soup cans. One of the few areas that is easy to change is diet. Older adults don't eat enough protein. 

Rei Otsuka and his colleagues have shown that greater protein intake improved muscle mass for men but not for women, which might have to do with menopause and the role of estrogen (especially estradiol). Women have it worse, since the loss of estradiol increases fat, decreases bone density, as well as muscle mass and muscle strength. All of these factors significantly contribute to the development of a condition termed “sarcopenic obesity.” It is that much harder for women to retain their muscles. But diet and exercise still seem to help, and increasing protein intake seems to help.

Keisuke Sakurai and his team compared a high-carbohydrate (HC) diet mainly composed of cereal against a protein-balanced (PB) diet with high intake of legumes, vegetables, seafood, meat, and eggs. Cognitive function was significantly higher in the PB group than in the HC group in a Japanese group. 

What is good for muscles is also good for the brain. A healthy body means a balanced diet and staying as active as you can.  Addressing sarcopenia might also prevent falling. Improving balance and flexibility by strengthening core muscles (chest, back, belly, hips, glutes, and thighs) and careful stretching can help prevent falls, a major cause of disability and death. Avoiding falls can be as simple as wearing stable shoes and having well-lit paths, to maintaining strength and flexibility. However active you are, don’t use ladders and perform other risky actions.