Saturday, December 24, 2016

Reversing Fifty Years of Progress in Life Expectancy

 Between 2014 and 2015 there was a sudden spike in death showing up in country reports. No one was expecting this increase.

People started dying earlier.  Not by much maybe 2 or 3 months earlier but it was significant. The first wave of national statistics was quickly followed by questions as to why. The first explanation related to local conditions, relating the upturn in death to local economic or weather conditions. Until it emerged this increase was not just a national event but an international phenomenon. Most industrialized countries showed a similar spike in death but for different population groups. This was global.

And the surprising detail that came out of all these countries mortality was that the increase in death seem to affect primarily older AND younger adult populations. With some exceptions, however, older people were dying earlier than at previous years. Small but significant increases in early death among older adults throughout industrialized countries.

For example, according to the Russian State Statistics Service (Rosstat), in the first quarter of 2015 they saw death grow by 5.2 percent compared to the same period last year, with a 22-percent rise in the death rate among those suffering from respiratory illnesses followed by diseases of the digestive system (10 percent), infectious diseases (6.5 percent), and blood circulation disorders (5 percent). While infant death, and death from murder and suicide, were falling. One of the clues for this increased death was that most of the deaths were brought about by respiratory diseases caused by common cold, flu and pneumonia.

In the United States, Anne Case and Angus Deaton wrote about the long-term increase specifically for one group of Americans, White adults. Although from 1978 to 1998, the mortality rate for US Whites aged 45–54 fell by 2% per year on average—which matched the average for other industrialized countries—after 1998, while the rest of the industrialized countries continued to show a 2% annual decline in mortality, in the USA the 45-54 age group showed half a percent annual increase. Reversing decades of progress in lowering mortality, there was a marked increase in death of middle-aged White men and women in the United States between 1999 and 2013. For three groups in particular those aged (with highest mortality first) 45-49, 56-59 and 50-54.  Among American older adults, mortality held constant or improved over this period. This increase for Whites was largely accounted for by increasing death from drug and alcohol poisonings, suicide, and chronic liver diseases including cirrhosis and was especially severe for those with less education.

Ill health in the United States remains an individual economic issue. Where for example maternal death is twice that of our neighbors in Canada despite the fact that we pay twice as much on health than Canadians. Americans get a very poor return for their health care contribution. The increase in death reflected an underlying decline in self-reported health, mental health and ability to conduct activities of daily living. Furthermore, there was an increases in reports of chronic pain and inability to work, as well as clinically measured deteriorations in liver function. All these indicators point to growing distress in this White population.  Although there are some methodological criticisms—age adjustment as populations change—the central thesis is solid, that in the USA middle-aged Whites have higher mortality increases than other populations. And surprisingly phenomenon is that this increase is still growing.

Across the Atlantic, in the United Kingdom, 2015 saw the largest rise in the number of recorded deaths in England and Wales in over a decade. Although the higher mortality peaked during winter it remained slightly above the five-year average for the rest of the year. By 2016 mortality was running at around 3.8% above the 5-year average, but again without accounting for population age changes. This increase was driven largely by increased mortality in over 75 year olds (83% of the increase). The cause being ascribed to dementia and respiratory diseases, including colds, flu and pneumonia.  A similar increase was experienced in many other European countries. It is normal for mortality to peak during winter season, especially for older populations—older adults are more prone to cold weather—but it is not only cold weather that was killing older adult. In Europe in July 2016 there has been observed a slight increased mortality among elderly in all countries, the most significant being in France and in Portugal since the beginning of July, increases which started during high temperatures.

Although we need to be cautious about extrapolating form single year data or using single methodologies as this might be an errant fluctuation. Something spikes in mortality occur naturally because of a convergence of many separate factors. Because this is a reversal of a trend—where other than increases in mortality due to wars, life expectancy has been improving for nearly a century—any reversal warrants attention.

Some researchers have argued for a social status/class causing the increase in deaths. Especially in the USA where the spike in deaths occurred among less educated White residents. The downturn in the economy after 2008—although it affected minorities more severely—for the White population the change was dramatic and unexpected. Minorities have had some time to become acclimatized to this depression. This is a good argument except that it does not explain all of the data, especially the U.K. data.

The U.K. mortality spike occurred in all areas of the country except for London. If the deaths were primarily driven by poverty then we should see poorer counties reporting higher deaths, which they do, but not consistently. Because of the inconsistency in deaths, there seem to be other variables at play. Since the increase in deaths is also a global phenomenon it could be the start of a growing trend and it might be worthwhile exploring other global factors other than economic—which is important but not a comprehensive answer.

Since these increased deaths are primarily caused by influenza and pneumonia—the main killers for older adults—there might be environmental factors at play. Although we should see a growing increase in deaths because our population is aging, these yearly fluctuations might be made worse by an increase in both the prevalence of bacteria and viruses and our reduced resilient to these new infections.

Global climate change and less effective anti-biotics together with a more vulnerable population—both older and perhaps less resilient because of poverty—might accelerate deaths.  Again, although these are small shifts in trends they are unique enough to warrant serious monitoring. The reversal of half a century of progress in life expectancy might herald a new way of looking at diseases that embraces a more central public health role. We might see that to address health we might have to look at the environment better. We shall have to wait and see how and when we continue to die.


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Additional resources:
The role of excess winter mortality in recent years Stephen Richards (Longevitas)

Russian statistics from: http://rbth.com/society/2015/05/26/experts_puzzled_by_sudden_rise_in_russias_mortality_rate_46363.html

References
Case, A., & Deaton, A. (2015). Rising morbidity and mortality in midlife among white non-Hispanic Americans in the 21st century. Proceedings of the National Academy of Sciences, 112(49), 15078-15083.

Gelman, A., & Auerbach, J. (2016). Age-aggregation bias in mortality trends. Proceedings of the National Academy of Sciences, 113(7), E816-E817.



© USA Copyrighted 2016 Mario D. Garrett  

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